
Biomedical engineers at the Massachusetts Institute of Technology (MIT) have developed specialized lipid nanoparticles capable of reprogramming immune cells directly inside the body to eliminate tumors and reverse autoimmune damage. Unlike conventional CAR-T therapies that require weeks of costly external laboratory cell engineering, the new approach delivers genetic instructions straight to natural killer (NK) cells via a single injection. In preclinical models, the treatment wiped out malignant T-cell cancers and healed autoimmune liver inflammation.