A two-decade-long study conducted by Boston University scientists revealed that a 30% reduction in caloric intake slows down brain aging processes. This work, featured in Aging Cell, illuminates how dietary energy intake affects cognitive performance in later life.
Researchers at Boston University have determined that maintaining a diet that is 30 percent less caloric over an extended period can mitigate the natural aging of the brain. This specific investigation spanned twenty years and its findings were recently presented in the journal Aging Cell (AC). The published paper details the outcomes derived from this long-term experiment.
The investigation uncovered that animals subjected to a caloric restriction of one-third over several decades exhibited a healthier metabolic state within their brain cells. Furthermore, these animals demonstrated elevated activity in genes responsible for producing myelin, the protective sheath surrounding nerve fibers.
Employing advanced single-nucleus sequencing technology, investigators ascertained that lowering the energy density of the diet favorably impacted the operation of metabolic pathways and lessened occurrences of age-related alterations within the cells of the brain’s white matter. The study’s authors posit that this type of “metabolically youthful” cellular environment is crucial for preserving cognitive capabilities.
These findings furnish compelling evidence suggesting that sustained dietary adjustments can decelerate cellular aging in the brain of complex organisms and may possibly influence cognitive well-being in advanced age.
Previously, researchers had established a correlation between increased muscle mass, reduced visceral fat levels, and a biologically “younger” brain age.
We previously reported on how physician Viktor Lishin shared insights for maintaining intellectual sharpness during winter. His advice highlighted the significance of Vitamin D and various B vitamins in sustaining focus and intellectual function during colder months. He also stressed the importance of minerals such as magnesium and lithium, emphasizing that proper gastrointestinal function is necessary for overall health and sustained mental activity.
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