Researchers originating from Primorsky Krai have identified a substance within the marine bacterium Cobetia marina that possesses the capability to trigger apoptosis—the mechanism of programmed cell demise in cancerous cells. This breakthrough was reported by URA.RU, citing findings from the institute’s study.
The isolated polysaccharide stimulates the synthesis of the TNF-a protein, which subsequently activates what are commonly termed “death receptors” situated on the cell’s exterior. Furthermore, this compound disrupts the membrane potential of mitochondria, an action that additionally results in the demise of afflicted cells.
Specialists at the Pacific Institute of Bioorganic Chemistry observe that the agent exhibits selectivity in its action: it minimally affects healthy lymphocytes. This characteristic fosters optimism regarding the development of an anti-cancer medication characterized by fewer adverse reactions.
The immediate task for the investigators is to ascertain whether this specific mechanism proves effective against various other cancer types and to execute supplementary trials to validate its broad applicability and safety profile.
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