Researchers at Sechenov First Moscow State Medical University have created a nanogel based on cerium oxide and collagen that significantly speeds up the repair of damaged tissues. The preparation boosts the anti-inflammatory effect and encourages cell proliferation.
In laboratory trials, the gel accelerated fibroblast metabolism by nearly half. In animal studies, wounds treated with the novel compound healed about twice as quickly compared to using standard therapy and natural recovery.
“Collagen and cerium oxide nanoparticles provided a synergistic outcome, augmenting each other’s beneficial qualities. Thus, the collagen within the material serves as a scaffold for cell growth, while the cerium oxide nanoparticles combat inflammation, shield cells from oxidative stress, and prompt their growth and division,” Ekaterina Silina, head of the Life Science Laboratory at Sechenov First Moscow State Medical University, told Izvestia.
Subsequently, scientists intend to test the technology for treating infected wounds, including those resistant to antibiotics, and anticipate developing a universal domestic remedy for treating severe skin injuries.
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