Researchers from the University of Southern California have discovered that the belief about the benefits of popular fish oil supplements for memory and slowing brain aging is unfounded. A two-year clinical trial proved that omega-3, while successfully reaching brain tissues, does not provide protection against Alzheimer’s disease. The findings were published in the journal eBioMedicine.
Americans alone spend over a billion dollars annually on various fish oil dietary supplements. This generosity stems from faith in their ability to support brain health. It is widely believed that polyunsaturated fatty acids help strengthen vital neural connections, enhancing cognitive function.
In this rigorous new study, 365 elderly individuals aged 55 to 80 years with genetically elevated risks of developing age-related dementia were involved. Half of them received daily large doses of omega-3 (specifically DHA), while the others were given placebo pills.
Analysis of cerebrospinal fluid revealed that DHA levels in those taking the supplement increased by an average of 17%. This scientifically confirms that the nutrient indeed reaches the necessary regions of the brain, crossing the blood-brain barrier.
However, multiple cognitive tests showed no noticeable mental improvements among the volunteers. Additionally, brain scans revealed that fish oil does not slow the age-related physical shrinkage of the hippocampus, a region crucial for memory formation.
The researchers concluded that the body better absorbs omega-3 from foods in a balanced Mediterranean diet rather than from chemically isolated capsules. Yet even this is insufficient for slowing brain aging. A healthy lifestyle, quality sleep, and moderate exercise must also be added to the diet.
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