A groundbreaking neurology study published today reveals that Alzheimer’s disease mutations can directly impair the peripheral nervous system long before classic cognitive decline or memory loss sets in. Researchers found that cellular transport disruptions in nerves outside the brain and spinal cord cause early motor and sensory deficits independently of central brain damage. The discovery suggests that future Alzheimer’s therapies must target the entire nervous system—not just the brain—to preserve physical mobility and protect long-term cognitive health.
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