Obesity affects the male and female body in distinct ways, consequently escalating the risks for various ailments. This conclusion was reached by researchers at Dokuz Eylül University, as reported by the EASO portal.
The study revealed that excess weight in men more frequently leads to the accumulation of visceral fat. This type of fat surrounds internal organs, bringing about heightened risks for cardiovascular and metabolic disorders. In women, higher cholesterol levels and noticeable inflammatory processes are more commonly observed, which contributes to an increased probability of diabetes and heart conditions.
For this investigation, specialists examined data from over 1100 obese patients. Men exhibited greater waist circumference measurements and blood pressure readings, even when their Body Mass Index fell within the optimal range. Elevated levels of liver enzymes and triglycerides—indicators of metabolic dysfunction and potential liver damage—were also more frequently detected in them.
Conversely, women tended to show elevated total and “bad” cholesterol, alongside markers for systemic inflammation. This suggests a different pathway in the development of complications, one linked to immune system activity.
The scientists believe these disparities are largely attributable to hormonal influences. Female sex hormones dictate fat distribution patterns and intensify inflammatory responses, whereas in men, fat tends to deposit around the visceral organs.
Obesity stands out as a primary driver of chronic disease risk. Experts estimate that metabolic syndrome is currently diagnosed in a significant proportion of the adult population. This condition encompasses abnormalities such as elevated blood pressure, high sugar levels, and increased cholesterol.
The authors emphasize that this new information will be valuable for crafting more precise and tailored obesity treatment strategies that account for the patient’s sex.
About the Author
