Medical researchers at Hoag have announced a world-first breakthrough in early ovarian cancer detection after identifying a distinct molecular warning signal in the bloodstream that flags precancerous lesions. The biomarker detects serous tubal intraepithelial carcinoma (STIC)—the earliest cellular precursor to high-grade serous ovarian cancer, which is typically diagnosed only at advanced stages. Scientists say the discovery paves the way for routine, non-invasive liquid biopsy screening capable of catching the disease years before invasive tumors develop.
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